Pharmikos Pharmacology Consultant Scientific analysis of therapeutic and side effects of drugs
 
Respiratory Depression, Opiates, Opioids, Fentanyl, Oxycodone (Oxycontin, Percocet, Percodan, Roxicodone, Tylox), Hydrocodone (Lorcet, Lortab, Vicodin)
Toxicology, Pharmacology, Neurotoxicology, Neuropharmacology

Anaphylaxis / Drug Allergy - immune reaction to drugs which can result in life-threatening conditions
Cognitive Impairment / Memory Disruption -many medications needed to be used chronically may cause impaired cognitive performance to the point that they restrict a person’s ability to carry out professional duties.
Myalgia - muscle pain which may be a warning sign of a serious condition
Neuroleptic Malignant Syndrome -hyperthermia with rhabdomyolysis caused by neuroleptic and antipsychotic drugs
Neuropathy – degeneration usually of peripheral sensory, motor, and/or autonomic nerves, caused by genetic factors, infection, or use of some medications
Opiate-induced Hypoxia or Respiratory Depression - Slightly high dose of opioid analgesics cause Respiratory Depression which can lead to death or hypoxic brain injury
Ototoxicity / Vestibulopathy - Gentamicin and other Antibiotics may cause Tinnitus and Cochlear degeneration) and deafness.
QTc Interval Prolongation, Torsades de Pointes - Arrhythmias and sudden death – changes in cardiac rhythm caused by drugs including Thioridazine (Mellaril), Mesoridazine (Serentil), Cisapride (Propulsid). Stroke.
Pseudomembranous Colitis - Intestinal condition caused by Clostridium difficile infection, usually nosocomial and resulting from improper antibiotic use
Serotonin Syndrome - Symptoms include cognitive (confusion, hypomania, hallucinations, agitation, headache, coma), autonomic (shivering, sweating, hyperthermia, hypertension, tachycardia, nausea, diarrhea) and somatic (myoclonus (muscle twitching), hyperreflexia (manifested by clonus), tremor).
Rhabdomyolysis - disruption of membranes of muscle cells resulting in release of creatine kinase and myoglobin, potentially culminating in kidney damage and death.
Stevens-Johnson Syndrome (Sjs) and Toxic Epidermal Necrolysis (Ten) - a rapid and serious autoimmune response usually triggered by use of a drug, usually marked by extensive blistering and sloughing of the skin.
Tardive Dyskinesia - largely irreversible involuntary movement disorder resulting usually from use of neuroleptic or antipsychotic drugs.

Therapeutic indications

Alzheimer Disease
Anxiety
Depression
Epilepsy
Hypoxic Brain Damage
Neurodegeneration
Neurotoxicity
Parkinson Disease
Schizophrenia
Stroke
Traumatic brain injury

Analgesics (Opioid / Opiate)

Hydrocodone (Lorcet, Lortab, Vicodin)
Morphine
Codeine
Demerol
     
The principal has experience as a Scientist performing Research or an Expert Witness testifying concerning these or related drugs. This list is not exhaustive or complete.
 
Pharmikos Inc ©2006 - 2010 | Consultant in Pharmacology & Toxicology
Adverse Drug Reaction Respiratory Depression, Opiates, Opioids, Fentanyl, Oxycodone (Oxycontin, Percocet, Percodan, Roxicodone, Tylox), Hydrocodone (Lorcet, Lortab, Vicodin) Rhabdomyolysis - disruption of membranes of muscle cells resulting in release of creatine kinase and myoglobin, potentially culminating in kidney damage and death. Cognitive Impairment / Memory Disruption Neuroleptic Malignant Syndrome -hyperthermia with rhabdomyolysis caused by neuroleptic and antipsychotic drugs Pseudomembranous Colitis - Intestinal condition caused by Clostridium difficile infection, usually nosocomial and resulting from improper antibiotic use Neuroleptic Malignant Syndrome -hyperthermia with rhabdomyolysis caused by neuroleptic and antipsychotic drugs Neuropathy QTc Interval Prolongation, Torsades de Pointes - Arrhythmias and sudden death – changes in cardiac rhythm caused by drugs including Thioridazine (Mellaril), Mesoridazine (Serentil), Cisapride (Propulsid). Stroke. Pseudomembranous Colitis - Intestinal condition caused by Clostridium difficile infection, usually nosocomial and resulting from improper antibiotic use Serotonin Syndrome Tardive Dyskinesia Ssri Antidepressants Expert Witness